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WebApr 15, 2024 · We devise a competition data-driven method to map RBD binding sites. We find that although antibody binding sites are widely dispersed, neutralizing antibody binding is focused, with nearly all highly inhibitory mAbs (IC 50 < 0.1 μg/mL) blocking receptor interaction, except for one that binds a unique epitope in the N-terminal domain. Many of ... WebMany drugs bind to proteins, primarily albumin, alpha-1 acid glycoprotein, and lipoproteins; protein binding limits distribution of free drug throughout the body. Albumin and total … chunk optimization
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