Cisplatin long term effects

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August undefined, 2024

WebApr 7, 2024 · Purpose To analyze the effect of cisplatin cycles on the clinical outcomes of patients with locally advanced cervical cancer (LACC) treated with concurrent chemoradiotherapy (CCRT). Methods This study included 749 patients with LACC treated with CCRT between January 2011 and December 2015. A receiver operating … WebThe application of esophagograms to evaluate early curative effects has a long history in China and has accumulated a lot of evidence. An esophagogram can show whether the outline of the esophagus is narrow and whether the esophageal mucosal folds are restored. ... Tang HR, et al. Long‐term results of paclitaxel plus cisplatin with concurrent ...

Carboplatin Side Effects: Common, Severe, Long Term - Drugs.com

WebApr 21, 2024 · If you’re receiving carboplatin or cisplatin chemotherapy, talk to your doctor about the risks to your hearing. Heart problems Chemotherapy can lead to high blood … WebNov 1, 2024 · Significant risks for long-term toxicities associated with cisplatin and platinum-based regimens were reported. The cumulative dose of cisplatin and … phillip yuill

Targeted therapy for cisplatin‐resistant lung cancer via …

WebDec 8, 2024 · painful or difficult urination accompanied by fever or chills red streaks along the injected vein shortness of breath stomach pain swelling of the feet and lower legs Rare Black, tarry stools blood in the urine pinpoint red spots on the skin unusual bleeding or bruising Other side effects of Doxorubicin WebCisplatin (DDP) has been a significant tumor chemotherapy against various solid malignant tumors, including lung adenocarcinoma, since it was approved by the Food and Drug Association in 1978.7Platinum chemotherapy drugs, represented by … WebJan 11, 2009 · I'm wondering what the long term effects of carboplatin could be? Carboplatin is a weaker analog of cisplatin. Carboplatin doesn't cross-link DNA as … phillip young attorney nashville

Platinum-Based Chemotherapy: Uses, Effectiveness, Side Effects

Chemoradiotherapy with paclitaxel liposome plus cisplatin for …

WebNov 16, 2016 · Factors influencing short- and long-term effects of cisplatin Overview of how different factors can influence long-term normal tissue effects after cisplatin (CDDP) treatment. CDDP causes DNA damage. Many cellular effects are mediated by p53 as part of the DNA damage response yielding long-term side effects. WebTherapeutic efficacy of cisplatin-based treatment of late stage urothelial carcinoma (UC) is limited by chemoresistance. To elucidate underlying mechanisms and to develop new approaches for overcoming resistance, we generated long-term cisplatin treated (LTT) UC cell lines, characterised their cisplatin response, and determined the expression of … phillip youmans ethnicityWebFatigue, nausea: Fatigue, nausea and vomiting are very common after chemotherapy treatments with cisplatin. Created for people with ongoing healthcare needs but benefits everyone. Learn how we can help 5.7k views Reviewed >2 years ago Thank Dr. Luis Villaplana and another doctor agree 2 thanks A 43-year-old member asked: phillip yoder

"WebFeb 9, 2024 · Being unusually disorganized Confusion Difficulty concentrating Difficulty finding the right word Difficulty learning new skills Difficulty multitasking Feeling of mental fogginess Short attention span Short-term memory problems Taking longer than usual to complete routine tasks Trouble with verbal memory, such as remembering a conversation " - Cisplatin long term effects

Cisplatin long term effects

Gemcitabine and cisplatin (GC) - Cancer Research UK

WebDec 31, 2024 · cough or hoarseness, accompanied by fever or chills fever or chills lower back or side pain, accompanied by fever or chills numbness or tingling in fingers or toes painful or difficult urination, accompanied by fever or chills pinpoint red spots on skin skin rash or itching unusual bleeding or bruising unusual tiredness or weakness Rare WebRapid DDP resistance is the main obstacle to recovery during long‐term follow‐up of lung adenocarcinoma patients, 10 , 11 with an overall five‐year survival of just 16%. 12 Therefore, improving the efficacy of DDP chemotherapy and sequential treatment after the failure of the DDP chemotherapy is crucial to saving patient lives.

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WebFatigue, nausea: Fatigue, nausea and vomiting are very common after chemotherapy treatments with cisplatin. Created for people with ongoing healthcare needs but benefits …

WebApr 17, 2024 · For patients treated with the chemotherapeutic drug cisplatin, one common consequence of treatment is permanent hearing loss. Reported rates of cisplatin ototoxicity vary widely, though it is believed that at least half of all patients treated with cisplatin will suffer hearing loss. WebApproximately 20 to 40% of long-term TCS experience symptoms of peripheral neuropathy after cisplatin-based chemotherapy [ 28, 29, 69 ]. Common clinical manifestations of peripheral neuropathy include numbness, tingling, and a decrease in vibratory sense in distal extremities [ 70 ].

WebCisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in kidney function, as manifested by a decline in the glomerular filtration rate (GFR), can be dose limiting. WebLong-term vascular toxicities associated with chemotherapy include Raynaud's phenomenon, acute myocardial infarction and cerebrovascular events. Bleomycin is thought to be the most important drug in the pathogenesis of Raynaud's phenomenon, while cisplatin is the most likely agent involved in myocardial infarction.

WebSep 15, 2024 · Cisplatin Injection (cisplatin injection (cisplatin (cisplatin injection) injection) ) is a sterile aqueous solution, available in 50, 100 and 200 mL multiple dose …

WebMar 12, 2024 · The majority also reported cisplatin as a risk factor. In addition, two non-eligible studies showed an association of a longer follow-up period with glomerular dysfunction.Twenty-two out of 52 studies, including 851 participants, studied proteinuria, which was present in 3.5% to 84% of participants. phillip yoxallWebNov 17, 2024 · blistering, peeling, or loosening of the skin cough or hoarseness dark urine diarrhea difficult breathing drowsiness joint or muscle pain loss of appetite lower back or side pain muscle tremors nausea or vomiting rapid, deep breathing red, irritated eyes red skin lesions, often with a purple center restlessness seizures stomach cramps tsa approved spray bottleWebSerum platinum levels and cisplatin induced ototoxicity among pediatric germ cell tumor survivors ... Abstract. Platinum-based chemotherapy is commonly used to treat germ cell tumors (GCT) but can cause detrimental health effects, including ototoxicity and tinnitus. ... (GaMETES) and invited to participate in a longitudinal study to learn more ... phillip youngerWebTherapeutic efficacy of cisplatin-based treatment of late stage urothelial carcinoma (UC) is limited by chemoresistance. To elucidate underlying mechanisms and to develop new … phillip zepp finraWebSep 18, 2024 · NCBI Bookshelf tsa approved wheelchair padsWebConclusions: Renal function before and after cisplatin treatment is an important determinant of long-term Pt exposure. Known long-term effects of testicular cancer treatment, such as paraesthesia, hypogonadism, hypercholesterolaemia and hypertension, are associated with long-term circulating Pt exposure. phillip zamora and tanya nelsonWebFeb 24, 2024 · Long Term Side Effects of Chemotherapy for Cancer. Heart Damage. Chemotherapy can cause cardiac effects early in treatment, but in some cases, the … tsa approved swiss army knife