Phospho s727

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August undefined, 2024

WebWestern blot - Phospho-STAT3-S727 Rabbit pAb (AP0474) Western blot analysis of extracts of various cell lines, using Phospho-STAT3-S727 antibody (AP0474) at 1:1000 dilution.HepG2 cells and C6 cells were treated by PMA/TPA (200 nM) at 37℃ for 30 minutes after serum-starvation overnight.HepG2 cells were treated by CIP (20uL/400ul) at 37℃ for ... WebHere, we studied the role of STAT3 activation on tyrosine 705 (Y705) and serine 727 (S727) in glioma radioresistance. This study explored STAT3 phosphorylation on Y705 (pSTAT3-Y705) and S727 (pSTAT3-S727) in glioma cell lines and in clinical samples. Radiosensitizing effect of STAT3 activation down-modulation by Gö6976 was explored.

Activation of Signal Transducer and Activator of Transcription 3 ...

WebOct 30, 2006 · In vivo analyses of S727 of Stat1 and Stat3 using knock-in mouse models showed that S727 plays important physiological roles [13], [14]. However, the biochemical function underlying the physiological importance of the phospho-serine and conserved LPMSP motif is not completely understood. WebHuman Phospho-HSP27 (S78/S82) Antibody Summary. Species Reactivity. Human. Specificity. Detects human HSP27 when dually phosphorylated at S78/S82 in Western … share code contact number

Recombinant Anti-STAT1 (phospho S727) antibody …

WebA phospho specific peptide corresponding to residues surrounding Serine 727 of human Stat-1 was used as an immunogen. This antibody only … WebSep 30, 2008 · S727 phosphorylation enhances the transcriptional activities of Stat3, whereas mutations of S727 compromise Stat3 transactivational activity and downstream effects ( 8 ). Cooperation of both tyrosine and serine phosphorylation is necessary for full activation of Stat3 ( 4 ). WebHuman/Mouse Phospho-Stat 1 (S727) and Total Stat 1 ELISA RayBiotech The store will not work correctly in the case when cookies are disabled. JavaScript seems to be disabled in … pool paint for walk around deck

Human Phospho-STAT3 (S727) Antibody MAB4934: R&D …

Phospho-Ser727 of STAT3 regulates STAT3 activity by …

WebPhospho S727 (2) Phospho S51 (1) Asymmetric DiMethyl R3 (1) MonoMethyl R26 (1) Phospho S380 (1) Symmetric DiMethyl R2 (1) Phospho S33 (1) Acetyl K23 (1) Asymmetric DiMethyl R8 (1) DiMethyl K14 (1) MonoMethyl R17 (1) MonoMethyl R8 (1) MonoMethyl R3 (1) Phospho S455 (1) Phospho Thr4 (1) Phospho S259 (1) Phospho S957 (1) Phospho … WebCitations: (293) The Phospho-Stat3 (Ser727) Antibody from Cell Signaling Technology is a Rabbit Polyclonal antibody to STAT3. This antibody recognizes Human, Mouse, and Rat antigen. The Phospho-Stat3 (Ser727) Antibody has been validated for the following applications: Precipitation, ChIP, Immunoprecipitation, and Western Blot. pool paintersWebProduct Name Phospho-STAT3(S727) Rabbit mAb; Host Species Rabbit ; Clonality Monoclonal ; Clone No. SY24-09 Purification ProA affinity purified; Applications WB, ICC/IF, IHC, IP; Species Reactivity Hu, RtMs; Immunogen Description Synthetic phospho-peptide corresponding to residues surrounding Ser727 of human STAT3.; Alternative Names … pool painting gold coast

"WebJan 11, 2012 · It has been shown that Ser727 of STAT3 is phosphorylated by various kinases, including mitogen-activated kinases (MAPK), H7-sensitive kinase, protein kinase Cδ, cyclin-dependent kinase 5 (CDK5), the mammalian target of rapamycin kinase (mTOR), nemo-like kinase (NLK), death-associated protein kinase 3 (DAPK3), and mitogen- and … " - Phospho s727

Phospho s727

STAT3 Serine 727 Phosphorylation: A Relevant Target to

WebHuman/Mouse Phospho-Stat 1 (S727) and Total Stat 1 ELISA. Be the first to review this product . RayBio® Human/Mouse Phospho-Stat 1 (S727) and Total Stat 1 ELISA Kit. This assay semi-quantitatively measures phosphorylated Stat 1 (Ser727) and Total Stat 1 in lysate samples. MANUAL / SDS. As low as $567.00. Size WebMay 4, 2024 · Serine kinases play a more nuanced role in regulating Stat3 due to direct Stat3 activation through S727 phosphorylation ( 16) by kinases such as mTOR ( 7) and others, which also have the potential for competing inhibitory effects from parallel downregulation of Stat3 tyrosine phosphorylation pathways ( 17 ).

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WebFeb 5, 2024 · TGFβ is the prototype of a large family of pluripotent cytokines with diverse effects on cellular proliferation, tumor growth, apoptosis, differentiation, fibrosis, anti-inflammation, and embryo development [1,2,3,4,5].The competence of TGFβ cytokine signaling plays an important role in determining lineage acquisition in cells of … WebPhospho-Stat1 (Ser727) Antibody detects endogenous levels of Stat1α only when phosphorylated at Ser727. This site is deleted in Stat1β. This antibody does not …

WebNov 13, 2024 · Phospho-S727 Stat3 localizes in mitochondria Recently, Larner and Levy groups described that phospho-Stat3 S727, but not phospho-Stat3 Y705, led to the accumulation of Stat3 in the... WebJan 15, 2001 · S727 phosphorylation of STAT1 in interferon-γ (IFN-γ)-treated mouse fibroblasts occurred without a need for p38 mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinases 1 and 2 or c-Jun kinases, and required both an intact SH2 domain and phosphorylation of Y701.

WebS727 phosphorylation is regulated directly by fibroblast growth factor/Erk signaling and crucial in the transition of mESCs from pluripotency to neuronal commitment. Loss of S727 phosphorylation resulted in significantly reduced neuronal differentiation potential, which could be recovered by a S727 phosphorylation mimic. ... WebStat transcription factors. Stat1 and Stat2 are induced by IFN-α and form a heterodimer which is part of the ISGF3 transcription factor comp

WebProduct Name Phospho-STAT3(S727) Rabbit mAb; Host Species Rabbit ; Clonality Monoclonal ; Clone No. SY24-09; Purification ProA affinity purified; Applications WB, …

WebThis protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. poolpaintscreen gmail.comWebSynthetic peptide within Human STAT1 (phospho S727). The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements. Database link: P42224 pool paint for hot tubsWebHuman Phospho-STAT3 (S727) Antibody Summary Species Reactivity Human Specificity Detects human STAT3 when phosphorylated at S727 in Western blots. Source Polyclonal Rabbit IgG Purification Antigen Affinity-purified Immunogen Phosphopeptide containing human STAT3 S727 site Accession # P40763 Formulation sharecodedWebUsing a combination of HepG2-stat3-knockdown cells reconstituted with various STAT3 mutants and protein kinase inhibitors, we showed that phospho-S727 has an intrinsic … share code dbs checkWebGet better batch-to-batch reproducibility with a recombinant antibody. Anti-STAT3 (phospho S727) antibody [E121-31] (ab32143) Research with … pool painting services near meWebHuman Phospho-STAT3 (S727) Antibody Summary Species Reactivity Human Specificity Detects human STAT3 when phosphorylated at S727. Source Monoclonal Mouse IgG 2B … pool paintings david hockneyWebPhospho-Stat3 (Ser727) Antibody recognizes endogenous levels of Stat3 only when phosphorylated at Ser727. The antibody does not significantly cross-react with the … pool paint in sprayer