Trientine wikipedia
WebTrientine. Trientine (triethylene tetramine dihydrochloride or trien) was introduced in 1969. It not only acts as a chelating agent and promotes urinary copper excretion, but also inhibits intestinal copper absorption through metallothionein induction. Trientine is an effective treatment for Wilson’s disease. WebTrientine, also known as triethylenetatramine or abbreviation TETA, is a highly selective divalent Cu(II) chelator and orphan drug that reverses copper overload in tissues. It was …
Trientine wikipedia
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WebTriethylenetetramine (TETA and trien), also called trientine (INN), is an organic compound with the formula [CH2NHCH2CH2NH2]2. This oily liquid is colorless but, like many amines, assumes a yellowish color due to impurities resulting from air-oxidation. Triethylenetetramine is soluble in polar solvents. WebThe world's first wiki where authorship really matters. Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. ... trientine N,N'-bis(2 …
WebTeratogenicity. Teratogenicity is the ability to cause defects in a developing fetus. It is a potential side effect of many drugs such as thalidomide. Many authors have reported that … WebFeb 1, 2024 · Niche uses. Turpentine is also added to many cleaning and sanitary products due to its antiseptic properties and its "clean scent". In early 19th-century America, …
WebIt was reported, that treatment with trientine inhibited tumor growth in a murine transplantation model using fibrosarcoma and induces apoptosis in tumor cells in vivo … WebTrientine. When treatment begins, doctors gradually increase the dose of chelating agents. People take higher doses of chelating agents until the extra copper in their body goes away. When Wilson disease symptoms improve and tests show that copper is at safe levels, your provider may prescribe lower doses of chelating agents as maintenance ...
WebTrientine is a related term of triethylenetetramine. In organic compound lang=en terms the difference between trientine and triethylenetetramine is that trientine is (organic …
Triethylenetetramine (TETA and trien), also known as trientine (INN) when used medically, is an organic compound with the formula [CH2NHCH2CH2NH2]2. The pure freebase is a colorless oily liquid, but, like many amines, older samples assume a yellowish color due to impurities resulting from air-oxidation. It is … See more Epoxy uses The reactivity and uses of TETA are similar to those for the related polyamines ethylenediamine and diethylenetriamine. It is primarily used as a crosslinker ("hardener") in See more Controversies In the United States, Valeant Pharmaceuticals International raised the price of its Syprine brand of TETA from $625 to $21,267 for 100 pills over five years. The New York Times said that this "egregious" price … See more • "Triethylenetetramine". Drug Information Portal. U.S. National Library of Medicine. • "Trientine hydrochloride". Drug Information Portal. U.S. National Library of Medicine. • "Trientine tetrahydrochloride". Drug Information Portal. U.S. National Library of Medicine. See more TETA is prepared by heating ethylenediamine or ethanolamine/ammonia mixtures over an oxide catalyst. This process gives a … See more TETA is a tetradentate ligand in coordination chemistry, where it is referred to as trien. Octahedral complexes of the type M(trien)L2 can adopt several diastereomeric … See more gfw title 2017WebTriethylenetetramine (TETA and trien), also known as trientine when used medically, is an organic compound with the formula [CH 2 NHCH 2 CH 2 NH 2] 2.The pure freebase is a … christ the king primary school thornabyWebSyprine. Indicated for treatment of Wilson disease in patients intolerant of penicillamine. 750-1250 mg/day PO divided q6-12hr. Increase dose if clinical response not adequate or … christ the king priory schuyler nebraska